The first exome wide association study in Tunisia: identification of candidate loci and pathways with biological relevance for type 2 diabetes

IntroductionType 2 diabetes (T2D) is a multifactorial disease involving genetic and environmental components. Several genome-wide association studies (GWAS) have been conducted to decipher potential genetic aberrations promoting the onset of this metabolic disorder. These GWAS have identified over 4...

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Principais autores:	Hamza Dallali, Wided Boukhalfa, Nadia Kheriji, Meriem Fassatoui, Haifa Jmel, Meriem Hechmi, Ismail Gouiza, Mariem Gharbi, Wafa Kammoun, Mehdi Mrad, Marouen Taoueb, Asma Krir, Hajer Trabelsi, Afef Bahlous, Henda Jamoussi, Olfa Messaoud, Abdelmajid Abid, Rym Kefi
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2023-12-01
Series:	Frontiers in Endocrinology
Assuntos:	type 2 diabetes exome wide association study Tunisian population gene-based analysis pathway-based analysis
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1293124/full
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