Anti-SARS-CoV-2 nucleoprotein IgA is associated with worse disease severity in critically ill COVID-19 pneumonia patients

While humoral responses to vaccination and infection have largely focused on IgG, there is an evolving literature on ways in which IgA may drive neutrophil activity in lung injury secondary to viral infections, including COVID-19. We evaluated 238 immune-naïve, critically ill patients in the first y...

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Autores principales:	David M. Brett-Major, Dylan S. George, Eric D. Morrell, Carmen Mikacenic, Julie M. Carstens, Laura E. Evans, Mark M. Wurfel, Pavan K. Bhatraju, M. Jana Broadhurst
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-07-01
Colección:	Frontiers in Immunology
Materias:	COVID-19 critical care IgA IgG lung injury machine learning
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1870217/full
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