Overexpression of GDNF in Spinal Cord Attenuates Morphine Analgesic Tolerance in Rats with Bone Cancer Pain

Bone cancer pain (BCP) is one of the typical and distressing symptoms in cancer patients. Morphine is a widely used analgesic drug for BCP; however, long-term morphine administration will lead to analgesic tolerance. Our previous study indicated that spinal glial cell line-derived neurotrophic facto...

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Bibliografische Detailangaben

Hauptverfasser:	Wei Xu, Zhuofeng Ding, Zongbin Song, Jian Wang, Jie Zhang, Wangyuan Zou
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-09-01
Schriftenreihe:	Brain Sciences
Schlagworte:	bone cancer pain morphine tolerance glial cell line-derived neurotrophic factor MOR spinal
Online-Zugang:	https://www.mdpi.com/2076-3425/12/9/1188
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