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Calciprotein particles induce arterial stiffening ex vivo and impair vascular cell function

Abstract Calciprotein particles (CPPs) are an endogenous buffering system, clearing excessive amounts of Ca2+ and PO4 3- from the circulation and thereby preventing ectopic mineralization. CPPs circulate as primary CPPs (CPP1), which are small spherical colloidal particles, and can aggregate to form...

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Principais autores: Cédric H. G. Neutel, Callan D. Wesley, Cindy van Loo, Céline Civati, Freke Mertens, Michelle Zurek, Anja Verhulst, Isabel Pintelon, Winnok H. De Vos, Bart Spronck, Lynn Roth, Guido R. Y. De Meyer, Wim Martinet, Pieter-Jan Guns
格式: Artigo
語言:Inglês
出版: Nature Portfolio 2024-10-01
叢編:Communications Biology
在線閱讀:https://doi.org/10.1038/s42003-024-06895-y
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