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Behavior of tetrahydrolipstatin in biological model membranes and emulsions

Tetrahydrolipstatin (orlistat) (S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl]dodecyl N-formyl-L-leucinate, a potent inhibitor of pancreatic lipase, is hydrophobic, amphipathic, and water-insoluble. It binds irreversibly to pancreatic lipases and inhibits fat absorption. The focus of this investigat...

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Bibliografische gegevens
Hoofdauteurs: J Ko, D M Small
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 1997-08-01
Reeks:Journal of Lipid Research
Online toegang:http://www.sciencedirect.com/science/article/pii/S0022227520371728
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