Apical dehydration impairs the cystic fibrosis airway epithelium barrier via a β 1-integrin/YAP1 pathway
Dehydration of the airway epithelial cell surface, a hallmark of CF, increases plasma membrane tension, resulting in altered Hippo signaling associated with the loss of barrier function. Defective hydration of airway surface mucosa is associated with lung infection in cystic fibrosis (CF), partly ca...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2024-04-01
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| coleção: | Life Science Alliance |
| Acesso em linha: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202302449 |
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