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Engineering TATA-binding protein Spt15 to improve ethanol tolerance and production in Kluyveromyces marxianus

Abstract Background Low ethanol tolerance of Kluyveromyces marxianus limits its application in high-temperature ethanol fermentation. As a complex phenotype, ethanol tolerance involves synergistic actions of many genes that are widely distributed throughout the genome, thereby being difficult to eng...

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Gespeichert in:
Hauptverfasser: Pengsong Li, Xiaofen Fu, Shizhong Li, Lei Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-07-01
Schriftenreihe:Biotechnology for Biofuels
Schlagworte:
Global transcription machinery engineering (gTME)
TATA-binding protein
Spt15
Kluyveromyces marxianus
Ethanol tolerance
Fermentation
Online-Zugang:http://link.springer.com/article/10.1186/s13068-018-1206-9
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