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The population genetics of dN/dS.

Evolutionary pressures on proteins are often quantified by the ratio of substitution rates at non-synonymous and synonymous sites. The dN/dS ratio was originally developed for application to distantly diverged sequences, the differences among which represent substitutions that have fixed along indep...

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Autori principali: Sergey Kryazhimskiy, Joshua B Plotkin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2008-12-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC2596312?pdf=render
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