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An oropharyngeal gonorrhoea controlled human infection model: a provisional protocol using a novel Neisseria gonorrhoeae challenge strain [version 1; peer review: 1 approved, 2 approved with reservations]

Introduction Gonorrhoea is a sexually transmissable infection caused by Neisseria gonorrhoeae that causes a significant global burden of disease. Urogenital infection can result in long-term impacts on reproductive, perinatal, and neonatal health. Little progress has been made in the public health c...

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Main Authors: Wilhelmina M Huston, Jason A Roberts, Christopher K Fairley, Kate L Seib, Marcus Y Chen, Eric PF Chow, Deborah A Williamson, Jane S Hocking, James S McCarthy, Joshua Osowicki, Eloise Williams, David J Price, Georgina L Pollock, Dana de Kretser, Tim Crocker-Buque, Shivani Pasricha, Euzebiusz Jamrozik, Andrew Steer, Francesca Azzato, Danika L Hill, Joanna R Groom
Format: Artigo
Language:Inglês
Published: Wellcome 2025-11-01
Series:Wellcome Open Research
Subjects:
Controlled human infection model
gonorrhoea
sexually transmitted infection
study protocol
vaccine
antimicrobial resistance
eng
Online Access:https://wellcomeopenresearch.org/articles/10-636/v1
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