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Stealth Liposomes (PEGylated) Containing an Anticancer Drug Camptothecin: In Vitro Characterization and In Vivo Pharmacokinetic and Tissue Distribution Study

Numerous attempts to overcome the poor water solubility of cam ptothecin (CPT) by various nano drug delivery systems are described in various sources in the literature. However, the results of these approaches may be hampered by the incomplete separation of free CPT from the formulations, and this i...

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Principais autores: Durgaramani Sivadasan, Muhammad H. Sultan, Osama Ali Madkhali, Shahd Hassan Alsabei, Asia Abdullah Alessa
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-02-01
Serier:Molecules
Fag:
camptothecin
lipid film hydration
polyethylene glycol
encapsulation efficiency
colorectal cancer
pharmacokinetic study
Online adgang:https://www.mdpi.com/1420-3049/27/3/1086
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