Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub
Infection and tissue damage induces assembly of supramolecular organizing centres (SMOCs)), such as the Toll-like receptor (TLR) MyDDosome, to co-ordinate inflammatory signaling. SMOC assembly is thought to drive digital all-or-none responses, yet TLR activation by diverse microbes induces anything...
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| Principais autores: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications Ltd
2018-01-01
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| Serier: | eLife |
| Fag: | |
| Online adgang: | https://elifesciences.org/articles/31377 |
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