Jagged1 Is Altered in Alzheimer's Disease and Regulates Spatial Memory Processing
Notch signaling plays an instrumental role in hippocampus-dependent memory formation and recent evidence indicates a displacement of Notch1 and a reduction its activity in hippocampal and cortical neurons from Alzheimer's disease (AD) patients. As Notch activation depends on ligand availability, we...
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| Автори: | , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2017-08-01
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| Серія: | Frontiers in Cellular Neuroscience |
| Предмети: | |
| Онлайн доступ: | http://journal.frontiersin.org/article/10.3389/fncel.2017.00220/full |
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