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The non-pathogenic protozoon Leishmania tarentolae interferes with the activation of NLRP3 inflammasome in human cells: new perspectives in the control of inflammation

BackgroundInnate immune responses against infectious agents can act as triggers of inflammatory diseases. On the other hand, various pathogens have developed mechanisms for the evasion of the immune response, based on an inhibition of innate immunity and inflammatory responses. Inflammatory diseases...

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Main Authors: Francesca La Rosa, Ilaria Varotto-Boccazzi, Marina Saresella, Ivana Marventano, Giulia Maria Cattaneo, Ambra Hernis, Federica Piancone, Domenico Otranto, Sara Epis, Claudio Bandi, Mario Clerici
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
immunity responses
inflammasome pathway
Leishmania tarentolae
NLRP3
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1298275/full
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