CEP290 is essential for the initiation of ciliary transition zone assembly.
Cilia play critical roles during embryonic development and adult homeostasis. Dysfunction of cilia leads to various human genetic diseases, including many caused by defects in transition zones (TZs), the "gates" of cilia. The evolutionarily conserved TZ component centrosomal protein 290 (CEP290) is...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2020-12-01
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| Serier: | PLoS Biology |
| Online adgang: | https://doi.org/10.1371/journal.pbio.3001034 |
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