Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3‐only proteins Bim and Bmf

Abstract Anti‐apoptotic Bcl‐2 family members are critical for the regulation of haematopoietic stem and progenitor cell (HSPC) survival. Little is known about the role of their pro‐apoptotic antagonists, i.e. ‘BH3‐only’ proteins, in this cell compartment. Based on the analysis of cytokine deprivatio...

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Detalhes bibliográficos

Principais autores:	Verena Labi, Daniela Bertele, Claudia Woess, Denise Tischner, Florian J. Bock, Sven Schwemmers, Heike L. Pahl, Stephan Geley, Mirjam Kunze, Charlotte M. Niemeyer, Andreas Villunger, Miriam Erlacher
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer Nature 2012-11-01
coleção:	EMBO Molecular Medicine
Assuntos:	apoptosis Bcl‐2 protein family Bmf Bim haematopoietic stem cell transplantation
Acesso em linha:	https://doi.org/10.1002/emmm.201201235
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