Distinct Inflammatory Macrophage Populations Sequentially Infiltrate Bone‐to‐Tendon Interface Tissue After Anterior Cruciate Ligament (ACL) Reconstruction Surgery in Mice

ABSTRACT Macrophages are important for repair of injured tissues, but their role in healing after surgical repair of musculoskeletal tissues is not well understood. We used single‐cell RNA sequencing (RNA‐seq), flow cytometry, and transcriptomics to characterize functional phenotypes of macrophages...

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Detalhes bibliográficos

Principais autores:	Takayuki Fujii, Susumu Wada, Camila B. Carballo, Richard D. Bell, Wataru Morita, Yusuke Nakagawa, Yake Liu, Daoyun Chen, Tania Pannellini, Upneet K. Sokhi, Xiang‐hua Deng, Kyung Hyung Park‐Min, Scott A. Rodeo, Lionel B. Ivashkiv
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2022-07-01
coleção:	JBMR Plus
Assuntos:	SYSTEMS BIOLOGY ‐ BONE INTERACTORS OSTEOIMMUNOLOGY ANIMAL MODELS ORTHOPAEDICS INJURY/FRACTURE HEALING
Acesso em linha:	https://doi.org/10.1002/jbm4.10635
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