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The leaves of the seasoning plant Litsea cubeba inhibit the NLRP3 inflammasome and ameliorate dextran sulfate sodium-induced colitis in mice

The intracellular sensor NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome controls caspase-1 activity and the maturation and release of the cytokines interleukin (IL)−1β and IL−18. The NLRP3 inflammasome has attracted the attention of the pharmaceutical industry because it promot...

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Principais autores: Wei-Ting Wong, Chun-Hsien Wu, Lan-Hui Li, De-Yu Hung, Hsiao-Wen Chiu, Hsien-Ta Hsu, Chen-Lung Ho, Oleg V. Chernikov, Shu-Meng Cheng, Shih-Ping Yang, Chih-Hsin Chung, Kuo-Feng Hua, Chin-Fah Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-07-01
coleção:Frontiers in Nutrition
Assuntos:
NLRP3 inflammasome
Litsea cubeba
macrophages
dextran sulfate sodium-induced colitis
cytokines
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnut.2022.871325/full
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