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Preventive effect of nasal Timosaponin BII-loaded temperature-/ion-sensitive in situ hydrogels on Alzheimer’s disease

Objective: To study the preventive effect of Timosaponin BII (T-BII) -loaded temperature/ion-sensitive nasal in situ hydrogels (ISGs) on Alzheimer's disease (AD), its preparation technology, characteristics and in vivo effects were evaluated. Methods: The morphological and rheological properties wer...

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Principais autores: Ge Ou, Wenyuan Chen, Meiyan Yang, Qian Li, Yuanyuan Zhang, Delian Wan, Lina Du, Baiping Ma
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021-01-01
Serier:Journal of Traditional Chinese Medical Sciences
Fag:
Timosaponin BII
Alzheimer’s disease
In situ hydrogels
Intranasal administration
Online adgang:http://www.sciencedirect.com/science/article/pii/S2095754821000028
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