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TRIM25-mediated ferroptosis resistance is closely associated with poor prognosis in hepatocellular carcinoma

ObjectiveTRIM25 has been reported to promote hepatocellular carcinoma (HCC) cell survival by activating the Keap1-Nrf2 pathway. However, its expression profile in clinical HCC specimens and its potential role in regulating ferroptosis remain to be elucidated. This study aimed to determine the expres...

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Autores principales: Yulang Jiang, Peizhen Ma, Xuling Liu, Dong Li, Lili Xu, Ningning Liu, Mingyu Sun
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2026-04-01
Colección:Frontiers in Immunology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1792807/full
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