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Spheroids derived from the stromal vascular fraction of adipose tissue self-organize in complex adipose organoids and secrete leptin

Abstract Background Adipose tissue-derived stromal vascular fraction (SVF) harbors multipotent cells with potential therapeutic relevance. We developed a method to form adipose spheroids (AS) from the SVF with complex organoid structure and enhanced leptin secretion upon insulin stimulation. Methods...

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Huvudupphov: Fermín Robledo, Lila González-Hodar, Pablo Tapia, Ana-María Figueroa, Fernando Ezquer, Víctor Cortés
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2023-04-01
Serie:Stem Cell Research & Therapy
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Länkar:https://doi.org/10.1186/s13287-023-03262-2
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