The Effect of Overexpressed DdRabS on Development, Cell Death, Vesicular Trafficking, and the Secretion of Lysosomal Glycosidase Enzymes

Rab GTPases are essential regulators of many cellular processes and play an important role in downstream signaling vital to proper cell function. We sought to elucidate the role of novel D. discoideum GTPase RabS. Cell lines over-expressing DdRabS and expressing DdRabS N137I (dominant negative (DN))...

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Principais autores:	Azure Yarbrough, Katherine Maringer, Entsar J. Saheb, Sanaa Jawed, John Bush
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2018-05-01
Colecção:	Biology
Assuntos:	Dictyostelium RabS vesicular trafficking lysosomal enzymes β-glucosidase GTPase development cell death
Acesso em linha:	http://www.mdpi.com/2079-7737/7/2/33
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