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Phase modulation of insulin pulses enhances glucose regulation and enables inter-islet synchronization.

Insulin is secreted in a pulsatile manner from multiple micro-organs called the islets of Langerhans. The amplitude and phase (shape) of insulin secretion are modulated by numerous factors including glucose. The role of phase modulation in glucose homeostasis is not well understood compared to the o...

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Principais autores: Boah Lee, Taegeun Song, Kayoung Lee, Jaeyoon Kim, Seungmin Han, Per-Olof Berggren, Sung Ho Ryu, Junghyo Jo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC5325581?pdf=render
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