Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 ProductionSummary

Background & Aims: Gut bacterial sphingolipids, primarily produced by Bacteroidetes, have dual roles as bacterial virulence factors and regulators of the host mucosal immune system, including regulatory T cells and invariant natural killer T cells. Patients with inflammatory bowel disease displa...

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Autores principales:	Bin Bao, Youyuan Wang, Pavl Boudreau, Xinyang Song, Meng Wu, Xi Chen, Izabel Patik, Ying Tang, Jodie Ouahed, Amit Ringel, Jared Barends, Chuan Wu, Emily Balskus, Jay Thiagarajah, Jian Liu, Michael R. Wessels, Wayne Isaac Lencer, Dennis L. Kasper, Dingding An, Bruce Harold Horwitz, Scott B. Snapper
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2024-01-01
Colección:	Cellular and Molecular Gastroenterology and Hepatology
Materias:	Microbiota Sphingolipids ILC3 Cells IL22 Colitis
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2352345X24001048
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