Modified live vaccine strains of porcine reproductive and respiratory syndrome virus cause immune system dysregulation similar to wild strains

IntroductionPorcine reproductive and respiratory syndrome virus (PRRSV) emerged about 30 years ago and continues to cause major economic losses in the pork industry. The lack of effective modified live vaccines (MLV) allows the pandemic to continue.Background and objectiveWe have previously shown th...

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Hauptverfasser:	Katerina Stepanova, Miroslav Toman, Jana Sinkorova, Simon Sinkora, Sarka Pfeiferova, Helena Kupcova Skalnikova, Salim Abuhajiar, Romana Moutelikova, Jiri Salat, Hana Stepanova, Katerina Nechvatalova, Lenka Leva, Petra Hermanova, Mirka Kratochvilova, Blanka Dusankova, Marek Sinkora, Vratislav Horak, Tomas Hudcovic, John E. Butler
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-01-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	Porcine respiratory and reproductive syndrome virus thymocytes T-cell precursors T lymphocytes B lymphocytes animals
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1292381/full
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