Diagnostic value of quantitative MR spectroscopy metabolite ratios for Canavan disease

PurposeCanavan disease (CD) is a leukodystrophy marked by deficiency in the aspartoacylase enzyme and accumulation of N-acetyl aspartate (NAA) in the white matter. MRI and MRS are crucial diagnostic tools for CD. MRS shows a distinctive, significant elevation of the NAA peak, which is typically not...

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Bibliografske podrobnosti

Principais autores:	Majid Reza Tahsini, Marzena Wylezinska-Arridge, Mohammad Zare, Sasan Saket, Mohammad Aidin Farahvash, Mahdis Morovvati, Elham Rahimian, Sotirios Bisdas
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-07-01
Serija:	Frontiers in Radiology
Teme:	Canavan disease hypomyelinating disorders leukodystrophies magnetic resonance spectroscopy N-acetyl-aspartate (NAA)
Online dostop:	https://www.frontiersin.org/articles/10.3389/fradi.2026.1826170/full
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