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The structure of classical swine fever virus N(pro): a novel cysteine Autoprotease and zinc-binding protein involved in subversion of type I interferon induction.

Pestiviruses express their genome as a single polypeptide that is subsequently cleaved into individual proteins by host- and virus-encoded proteases. The pestivirus N-terminal protease (N(pro)) is a cysteine autoprotease that cleaves between its own C-terminus and the N-terminus of the core protein....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Keerthi Gottipati, Nicolas Ruggli, Markus Gerber, Jon-Duri Tratschin, Matthew Benning, Henry Bellamy, Kyung H Choi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS Pathogens
Online-Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24146623/pdf/?tool=EBI
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