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Investigating the Mechanism of Germinal Center Shutdown

Germinal centers (GCs) are transient structures where affinity maturation of B cells gives rise to high affinity plasma and memory cells. The mechanism of GC shutdown is unclear, despite being an important phenomenon maintaining immune homeostasis. In this study, we used a mathematical model to iden...

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Autors principals: Theinmozhi Arulraj, Sebastian C. Binder, Michael Meyer-Hermann
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-07-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2022.922318/full
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