RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev–Rev response element complex

The HIV-1 protein Rev controls a critical step in viral replication by mediating the nuclear export of unspliced and singly-spliced viral mRNAs. Multiple Rev subunits assemble on the Rev Response Element (RRE), a structured region present in these RNAs, and direct their export through the Crm1 pathw...

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主要な著者:	Bhargavi Jayaraman, David C Crosby, Christina Homer, Isabel Ribeiro, David Mavor, Alan D Frankel
フォーマット:	Artigo
言語:	Inglês
出版事項:	eLife Sciences Publications Ltd 2014-12-01
シリーズ:	eLife
主題:	HIV protein-RNA structure nuclear export
オンライン･アクセス:	https://elifesciences.org/articles/04120
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