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Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy?

In recent times, several investigations have been seeking an explanation for the great variability in both outcome and toxicity in cisplatin-based therapy through pharmacogenetic studies. These studies have focused on the genetic variability of therapeutic targets that could affect cisplatin respons...

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Detalles Bibliográficos
Principais autores: Juan Pablo Cayún Pellizaris, Ángela eRoco, Luis Abel Quiñones, Stephania eContreras, Jana eStojanova
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Genetics
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Acceso en liña:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00391/full
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