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Multi-epitope vaccine against nucleoprotein and envelopment polyprotein of Batai orthobunyavirus using molecular docking and molecular dynamics studies

Abstract Batai orthobunyavirus (BATV) is a mosquito-borne orthobunyavirus that affects both humans and animals, and currently no licensed vaccine is available. The aim of this study was to design a multi-epitope vaccine candidate against BATV using a computational vaccinology pipeline. Predicted B-c...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Muhammad Naveed, Muhammad Asim, Adeeba Ali, Sonia Amjad, Muhammad Nouman Majeed, Mengue Ngadena Yolande Sandrine, Nawal Al-Hoshani, Rania Ali El Hadi Mohamed, Maher S. Alwethaynani, Mai M. Almsaud
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2026-03-01
Schriftenreihe:Scientific Reports
Schlagworte:
Batai orthobunyavirus
Multi-epitope vaccine
Epitopes
Molecular docking
Toll-like receptor
Molecular dynamics simulation
Online-Zugang:https://doi.org/10.1038/s41598-026-41964-8
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