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Integrative analysis associates monocytes with insufficient erythropoiesis during acute Plasmodium cynomolgi malaria in rhesus macaques

Abstract Background Mild to severe anaemia is a common complication of malaria that is caused in part by insufficient erythropoiesis in the bone marrow. This study used systems biology to evaluate the transcriptional and alterations in cell populations in the bone marrow during Plasmodium cynomolgi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yan Tang, Chester J. Joyner, Monica Cabrera-Mora, Celia L. Saney, Stacey A. Lapp, Mustafa V. Nural, Suman B. Pakala, Jeremy D. DeBarry, Stephanie Soderberg, the MaHPIC Consortium, Jessica C. Kissinger, Tracey J. Lamb, Mary R. Galinski, Mark P. Styczynski
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2017-09-01
Schriftenreihe:Malaria Journal
Schlagworte:
Plasmodium cynomolgi
GATA1
Nonhuman primates
Relapse
Plasmodium vivax
Bone marrow
Online-Zugang:http://link.springer.com/article/10.1186/s12936-017-2029-z
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