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PD-1/PD-L1 immune checkpoint blockade in breast cancer: research insights and sensitization strategies

Abstract Immunotherapy targeting programmed cell death-1 (PD-1) and PD-L1 immune checkpoints has reshaped treatment paradigms across several cancers, including breast cancer. Combining PD-1/PD-L1 immune checkpoint blockade (ICB) with chemotherapy has shown promising efficacy in both early and metast...

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Principais autores: Menglei Jin, Jun Fang, Junwen Peng, Xintian Wang, Ping Xing, Kunpeng Jia, Jianming Hu, Danting Wang, Yuxin Ding, Xinyu Wang, Wenlu Li, Zhigang Chen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-11-01
Serier:Molecular Cancer
Fag:
Breast cancer
PD-1/PD-L1
Immune checkpoint blockade
Clinical trials
Biomarkers
Sensitization strategies
Online adgang:https://doi.org/10.1186/s12943-024-02176-8
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