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Multi-Factor Regulation of the Master Modulator LeuO for the Cyclic-(Phe-Pro) Signaling Pathway in Vibrio vulnificus

Abstract LeuO plays the role of a master regulator in the cyclic-L-phenylalanine-L-proline (cFP)-dependent signaling pathway in Vibrio vulnificus. cFP, as shown through isothermal titration calorimetry analysis, binds specifically to the periplasmic domain of ToxR. Binding of cFP triggers a change i...

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Bibliográfalaš dieđut
Váldodahkkit: Na-Young Park, In Hwang Kim, Yancheng Wen, Keun-Woo Lee, Sora Lee, Jeong-A Kim, Kwang-Hwan Jung, Kyu-Ho Lee, Kun-Soo Kim
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2019-12-01
Ráidu:Scientific Reports
Liŋkkat:https://doi.org/10.1038/s41598-019-56855-4
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