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Intratumoral CD103+CD8+ T cells predict response to neoadjuvant chemoimmunotherapy in advanced head and neck squamous cell carcinoma

Abstract Background Immune cell heterogenicity is known to determine the therapeutic response to cancer progression. Neoadjuvant chemoimmunotherapy (NACI) has shown clinical benefits in some patients with advanced head and neck squamous cell carcinoma (HNSCC), but the underlying mechanism behind thi...

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Principais autores: Siqi Ren, Tianjun Lan, Fan Wu, Suling Chen, Xue Jiang, Chuying Huo, Zitian Li, Shule Xie, Donghui Wu, Ruixin Wang, Yanyan Li, Lin Qiu, Guoxin Huang, Shurui Li, Xiaojuan Wang, Meifeng Cen, Tingting Cai, Zhaoyu Lin, Jinsong Li, Bowen Li
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2023-10-01
Serier:Cancer Communications
Fag:
CD103
CD8
head and neck squamous cell carcinoma
neoadjuvant chemoimmunotherapy
predictive marker
tumor‐infiltrating lymphocyte
Online adgang:https://doi.org/10.1002/cac2.12480
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