Does HLA-B27 Status Influence Ixekizumab Efficacy in Axial Spondyloarthritis? Results From the COAST-V, COAST-W, and COAST-X Trials

Abstract Introduction The human leukocyte antigen (HLA)-B27 is associated with axial spondyloarthritis (axSpA) and is a predictor of response to tumor necrosis factor inhibitors. However, limited data are available on HLA-B27 and interleukin-17 inhibitors. We evaluated the influence of HLA-B27 statu...

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Bibliografiska uppgifter

Huvudupphov:	John D. Reveille, Martin Rudwaleit, Proton Rahman, Jose A. Maldonado-Cocco, Marina Magrey, Rebecca Bolce, Khai Jing Ng, Theresa Hunter Gibble, Jeffrey Lisse, So Young Park, Andris Kronbergs, Victoria Navarro-Compán
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Adis, Springer Healthcare 2025-12-01
Serie:	Rheumatology and Therapy
Ämnen:	Axial spondyloarthritis HLA-B27 Ixekizumab Non-radiographic Radiographic
Länkar:	https://doi.org/10.1007/s40744-025-00810-5
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