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CSF Proteomic Alzheimer’s Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals

We recently discovered three distinct pathophysiological subtypes in Alzheimer’s disease (AD) using cerebrospinal fluid (CSF) proteomics: one with neuronal hyperplasticity, a second with innate immune system activation, and a third subtype with blood–brain barrier dysfunction. It remains unclear whe...

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Bibliografiske detaljer
Principais autores: Betty Marije Tijms, Johan Gobom, Charlotte Teunissen, Valerija Dobricic, Magda Tsolaki, Frans Verhey, Julius Popp, Pablo Martinez-Lage, Rik Vandenberghe, Alberto Lleó, José Luís Molinuévo, Sebastiaan Engelborghs, Yvonne Freund-Levi, Lutz Froelich, Lars Bertram, Simon Lovestone, Johannes Streffer, Stephanie Vos, ADNI, Kaj Blennow, Philip Scheltens, Henrik Zetterberg, Pieter Jelle Visser
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-08-01
Serier:Proteomes
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Online adgang:https://www.mdpi.com/2227-7382/9/3/36
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