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Effects of HOX family regulator-mediated modification patterns and immunity characteristics on tumor-associated cell type in endometrial cancer

Abstract Endometrial cancer (UCEC) is one of three major malignant tumors in women. The HOX gene regulates tumor development. However, the potential roles of HOX in the expression mechanism of multiple cell types and in the development and progression of tumor microenvironment (TME) cell infiltratio...

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Principais autores: JiaoLin Yang, JinPeng Li, SuFen Li, YuTong Yang, HuanCheng Su, HongRui Guo, Jing Lei, YaLin Wang, KaiTing Wen, Xia Li, SanYuan Zhang, Zhe Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2024-08-01
coleção:Molecular Biomedicine
Assuntos:
HOX gene
Endometrial cancer
Tumor microenvironment
scRNA-seq
Cancer-associated fibroblasts (CAFs)
Acesso em linha:https://doi.org/10.1186/s43556-024-00196-w
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