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Synapses, predictions, and prediction errors: A neocortical computational study of MDD using the temporal memory algorithm of HTM

IntroductionSynapses and spines play a significant role in major depressive disorder (MDD) pathophysiology, recently highlighted by the rapid antidepressant effect of ketamine and psilocybin. According to the Bayesian brain and interoception perspectives, MDD is formalized as being stuck in affectiv...

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Bibliografiset tiedot
Päätekijät: Mohamed A. Sherif, Mostafa Z. Khalil, Rammohan Shukla, Joshua C. Brown, Linda L. Carpenter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2023-02-01
Sarja:Frontiers in Psychiatry
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Linkit:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.976921/full
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