Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer

Advances in DNA- and RNA-based technologies have made gene therapy suitable for many lung diseases, especially those that are hereditary. The main objective of gene therapy is to deliver an adequate amount of gene construct to the intended target cell, achieve stable transduction in target cells, an...

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Detalles Bibliográficos

Principais autores:	Michael G. Katz, Anthony S. Fargnoli, Sarah M. Gubara, Kenneth Fish, Thomas Weber, Charles R. Bridges, Roger J. Hajjar, Kiyotake Ishikawa
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2019-02-01
Series:	Journal of Cardiovascular Development and Disease
Assuntos:	gene therapy lung cellular structure biological barriers viral vectors endotracheal route of delivery hereditary mutation
Acceso en liña:	https://www.mdpi.com/2308-3425/6/1/8
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