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Immunorecovered but Exhausted: Persistent PD-1/PD-L1 Expression Despite Virologic Suppression and CD4 Recovery in PLWH

<b>Background/Objectives:</b> While ART effectively suppresses HIV viremia, many PLWH exhibit persistent immune dysfunction. This study aimed to assess immune recovery and immune exhaustion (PD-1/PD-L1 expression) in newly diagnosed versus long-term ART-treated individuals. <b>Methods:</b> We analyz...

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Principais autores: Bogusz Aksak-Wąs, Karolina Skonieczna-Żydecka, Miłosz Parczewski, Rafał Hrynkiewicz, Filip Lewandowski, Karol Serwin, Kaja Mielczak, Adam Majchrzak, Mateusz Bruss, Paulina Niedźwiedzka-Rystwej
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-08-01
coleção:Biomedicines
Assuntos:
HIV
PD-1
immune reconstitution
immune exhaustion CD4
CD8
Acesso em linha:https://www.mdpi.com/2227-9059/13/8/1885
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