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Genome-based prediction of cross-protective, HLA-DR-presented epitopes as putative vaccine antigens for multiple Bordetella species

ABSTRACT Acellular pertussis vaccines protect against severe pertussis, but vaccine-induced immunity wanes over time. Prior animal studies showed that T-cell responses are integral to long-lasting immunity. Current pertussis vaccines also do not provide considerable protection against other species...

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Principais autores: Muktha S. Natrajan, Jesse M. Hall, Michael R. Weigand, Yanhui Peng, Margaret M. Williams, Mohamed Momin, Frederick Heath Damron, Purnima Dubey, Maria Lucia Tondella, Lucia C. Pawloski
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2024-01-01
叢編:Microbiology Spectrum
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在線閱讀:https://journals.asm.org/doi/10.1128/spectrum.03527-23
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