Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1,2,3-triazole-sulfonamide hybrids as antimicrobial and antiproliferative agents

Abstract Background Nitrogen heterocyclic rings and sulfonamides have attracted attention of several researchers. Results A series of regioselective imidazole-based mono- and bis-1,4-disubstituted-1,2,3-triazole-sulfonamide conjugates 4a–f and 6a–f were designed and synthesized. The first step in th...

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Автори:	Fawzia Faleh Al-blewi, Meshal A. Almehmadi, Mohamed Reda Aouad, Sanaa K. Bardaweel, Pramod K. Sahu, Mouslim Messali, Nadjet Rezki, El Sayed H. El Ashry
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMC 2018-11-01
Серія:	Chemistry Central Journal
Предмети:	1,2,3-Triazoles Sulfonamides Benzimidazoles Click synthesis Antimicrobial activity Antiproliferative activity
Онлайн доступ:	http://link.springer.com/article/10.1186/s13065-018-0479-1
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