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Prospective Analysis of urINe LAM to Eliminate NTM Sputum Screening (PAINLESS) study: Rationale and trial design for testing urine lipoarabinomannan as a marker of NTM lung infection in cystic fibrosis.

<h4>Background</h4>Routine screening for nontuberculous mycobacterial (NTM) lung disease is dependent on sputum cultures. This is particularly challenging in the cystic fibrosis (CF) population due to reduced sputum production and low culture sensitivity. Biomarkers of infection that do not rely on...

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Hlavní autoři: Kara M Calhoun, Emily Armantrout, Katie Poch, Silvia Caceres, Valerie K Lovell, Marion Jones, Kenneth C Malcolm, Brian Vestal, Emily Wheeler, Noel Rysavy, Jordan Manzer, Ibrahim Aboellail, Delphi Chatterjee, Jerry A Nick
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2025-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0309191
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