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Calorie restriction outperforms bariatric surgery in a murine model of obesity and triple-negative breast cancer

Obesity promotes triple-negative breast cancer (TNBC), and effective interventions are urgently needed to break the obesity-TNBC link. Epidemiologic studies indicate that bariatric surgery reduces TNBC risk, while evidence is limited or conflicted for weight loss via low-fat diet (LFD) or calorie re...

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Principais autores: Kristina K. Camp, Michael F. Coleman, Tori L. McFarlane, Steven S. Doerstling, Subreen A. Khatib, Erika T. Rezeli, Alfor G. Lewis, Alexander J. Pfeil, Laura A. Smith, Laura W. Bowers, Farnaz Fouladi, Weida Gong, Elaine M. Glenny, Joel S. Parker, Ginger L. Milne, Ian M. Carroll, Anthony A. Fodor, Randy J. Seeley, Stephen D. Hursting
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2023-10-01
Serier:JCI Insight
Fag:
Metabolism
Oncology
Online adgang:https://doi.org/10.1172/jci.insight.172868
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