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Preparation and characterization of rilpivirine solid dispersions with the application of enhanced solubility and dissolution rate

Rilpivirine (RPV) is a pharmaceutical drug used for the treatment of HIV infection. The drug is characterized with poor aqueous solubility and dissolution rate leading to low bioavailability of the drug. Hence, there is a need for the improvement of the solubility and dissolution of such drugs. In t...

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Hlavní autoři: Pavan kommavarapu, Arthanareeswari Maruthapillai, Kamaraj Palanisamy, Manasvi Sunkara
Médium: Artigo
Jazyk:Inglês
Vydáno: SpringerOpen 2015-03-01
Edice:Beni-Suef University Journal of Basic and Applied Sciences
Témata:
Rilpivirine
Solid dispersion
Dissolution rate
Drug release kinetics
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2314853515000116
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