Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC ^min/J Mice

The Eph receptors are the largest receptors tyrosine kinases (RTKs) family in humans and together with ephrin ligands constitute a complex cellular communication system often dysregulated in many tumors. The role of the Eph-ephrin system in colorectal cancer (CRC) has been investigated and different...

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Principais autores:	Miriam Corrado, Carmine Giorgio, Elisabetta Barocelli, Giuseppe Vittucci Marzetti, Anna Maria Cantoni, Rosanna Di Lecce, Matteo Incerti, Riccardo Castelli, Alessio Lodola, Massimiliano Tognolini
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2020-04-01
Series:	Pharmaceuticals
Assuntos:	Eph-ephrin system EphA receptors EphB receptors Eph antagonist UniPR129 APC <sup>min</sup>/J mice
Acceso en liña:	https://www.mdpi.com/1424-8247/13/4/69
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