Synthesis, effect of substituents on the regiochemistry and equilibrium studies of tetrazolo[1,5-a]pyrimidine/2-azidopyrimidines

An efficient synthesis methodology for a series of tetrazolo[1,5-a]pyrimidines substituted at the 5- and 7-positions from the cyclocondensation reaction [CCC + NCN] was developed. The NCN corresponds to 5-aminotetrazole and CCC to β-enaminone. Two distinct products were observed in accordance with t...

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Detalhes bibliográficos

Principais autores:	Elisandra Scapin, Paulo R. S. Salbego, Caroline R. Bender, Alexandre R. Meyer, Anderson B. Pagliari, Tainára Orlando, Geórgia C. Zimmer, Clarissa P. Frizzo, Helio G. Bonacorso, Nilo Zanatta, Marcos A. P. Martins
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Beilstein-Institut 2017-11-01
coleção:	Beilstein Journal of Organic Chemistry
Assuntos:	5-aminotetrazol azide–tetrazole equilibrium 2-azidopyrimidine β-enaminones tetrazolo[1,5-a]pyrimidine trifluoromethylatedtetrazolo[1,5-a]pyrimidines
Acesso em linha:	https://doi.org/10.3762/bjoc.13.237
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