Immunogenic arenavirus vector SIV vaccine reduces setpoint viral load in SIV-challenged rhesus monkeys

Abstract HIV affects more than 38 million people worldwide. Although HIV can be effectively treated by lifelong combination antiretroviral therapy, only a handful of patients have been cured. Therapeutic vaccines that induce robust de novo immune responses targeting HIV proteins and latent reservoir...

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Hlavní autoři:	Archana V. Boopathy, Bhawna Sharma, Anurag Nekkalapudi, Raphaela Wimmer, Maria Gamez-Guerrero, Silpa Suthram, Hoa Truong, Johnny Lee, Jiani Li, Ross Martin, Wade Blair, Romas Geleziunas, Klaus Orlinger, Sarah Ahmadi-Erber, Henning Lauterbach, Tariro Makadzange, Brie Falkard, Sarah Schmidt
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2023-11-01
Edice:	npj Vaccines
On-line přístup:	https://doi.org/10.1038/s41541-023-00768-x
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