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Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum.

Plasmodium spp parasites harbor an unusual plastid organelle called the apicoplast. Due to its prokaryotic origin and essential function, the apicoplast is a key target for development of new anti-malarials. Over 500 proteins are predicted to localize to this organelle and several prokaryotic bioche...

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Bibliografiske detaljer
Principais autores: Ellen Yeh, Joseph L DeRisi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2011-08-01
Serier:PLoS Biology
Online adgang:https://doi.org/10.1371/journal.pbio.1001138
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