Genome-wide accumulations of non-random adaptive point mutations drive westward evolution of Helicobacter pylori

Abstract Background For last seven decades we remained convinced that the natural point mutations occur randomly in the genome of an organism. However, our whole genome sequence analyses show that for the gastric pathogen Helicobacter pylori, which causes peptic ulcer and gastric cancer, accumulatio...

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Κύριοι συγγραφείς:	R. J. Retnakumar, Prakash Chettri, Sangey Chhophel Lamtha, K. C. Sivakumar, Priya Dutta, Pahil Sen, Sanjit Biswas, Nikita Agarwal, Angitha N. Nath, T. Barani Devi, Namrata Thapa, Jyoti Prakash Tamang, Santanu Chattopadhyay
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2025-04-01
Σειρά:	BMC Microbiology
Θέματα:	Helicobacter pylori CagA Genome Evolution Non-random point mutations
Διαθέσιμο Online:	https://doi.org/10.1186/s12866-025-03944-2
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